Because Rose Byrne recorded all her lines after filming, in order to have lines to react to, an earwig was placed inside Adam Devine's ear with and Actress/Voice-Over Artist Laurie Burke delivered Jexi's lines to him. However, sometimes the earpiece would malfunction. Co-Director Jon Lucas exclaimed that "there were times when Adam would just take the earbud out and do the whole scene without ever hearing anyone talking."
The film was originally to be titled, "Lexi," however the production was having legal issues getting that title cleared. So on the first day of filming, Adam Devine simply suggested flipping the "L" in Lexi to a "J" and thus the name Jexi was born.
The reason for Phil's lower legs being strangely hidden by socks when posing for a dick pic is because of the significant scarring Adam Devine has due to a childhood accident.
Access to filming locations was hampered by both an unusually heavy rainy season in San Francisco, as well as a government shutdown in early 2019, which blocked filmmakers' access to federally owned property in the city, such as Crissy Field in the Presidio - leading to many last minute re-writes and location changes.