After the series' cancellation, the Syfy channel had been rumored to be in talks to continue the series as a miniseries, but they never picked it up.
The Event was one of four new series screened at San Diego Comic-Con in July 2010, with The Hollywood Reporter saying the crowd response suggested "NBC's fall drama The Event came up a big winner."
Laura Innes was cast as Sophia Maguire, a role which was originally envisioned as male. She and and Lisa Vidal (First Lady Christina Martinez) had acted together previously - as lesbian lovers, Dr. Kerry Weaver and firefighter Lt. Sandy Lopez, in ER (Seasons 8-10). Blair Underwood came on board in early March 2010 in the role of President Eli Martinez, a role which was originally planned for a Hispanic actor.
The show's pilot episode is told almost entirely in retroversions to three different time frames. According to Nick Wauters, the show's creator, later episodes would use flashbacks more to develop the characters. "There will be big reveals and big clues in each episode," he said, promising that viewers would not have to wait too long for answers to questions raised. The last two episodes before and all episodes following the show's hiatus no longer featured flashbacks. Cast member Blair Underwood said regarding the removal of the flashbacks, "We had been jumping around a lot and doing flashbacks and that was confusing to people," and "So when we come back, that device is done with! We are now telling the story straight through so people can track it and follow it easier."