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- Using a crack team of doctors and his wits, an antisocial maverick doctor specializing in diagnostic medicine does whatever it takes to solve puzzling cases that come his way.
- The series follows Adrian Monk, a brilliant former San Francisco detective, who now consults the police as a private consultant whilst battling with an obsessive-compulsive disorder.
- The continuing misadventures of neurotic New York City stand-up comedian Jerry Seinfeld and his equally neurotic New York City friends.
- Two F.B.I. Agents, Fox Mulder the believer and Dana Scully the skeptic, investigate the strange and unexplained, while hidden forces work to impede their efforts.
- A faded television actor and his stunt double strive to achieve fame and success in the final years of Hollywood's Golden Age in 1969 Los Angeles.
- A thief who steals corporate secrets through the use of dream-sharing technology is given the inverse task of planting an idea into the mind of a C.E.O., but his tragic past may doom the project and his team to disaster.
- A young woman, destined to slay vampires, demons and other infernal creatures, deals with her life fighting evil, with the help of her friends.
- The doctors who work in the ER at the County General Hospital in Chicago grapple with ups and downs in their personal and professional lives while trying to give apt medical care to their patients.
- Professional writer and amateur sleuth Jessica Fletcher uses her intellect, charm, and persistence to get to the bottom of every crime she encounters.
- At the intersection of the near future and the reimagined past, waits a world in which every human appetite can be indulged without consequence.
- Secrets and truths unfold through the lives of female friends in one suburban neighborhood after the mysterious suicide of a neighbor.
- With his wife's disappearance having become the focus of an intense media circus, a man sees the spotlight turned on him when it's suspected that he may not be innocent.
- After a tragic accident, two stage magicians in 1890s London engage in a battle to create the ultimate illusion while sacrificing everything they have to outwit each other.
- Marty McFly, a 17-year-old high school student, is accidentally sent 30 years into the past in a time-traveling DeLorean invented by his close friend, the maverick scientist Doc Brown.
- Blacksmith Will Turner teams up with eccentric pirate "Captain" Jack Sparrow to save his love, the governor's daughter, from Jack's former pirate allies, who are now undead.
- An insurance salesman discovers his whole life is actually a reality TV show.
- An ancient struggle between two Cybertronian races, the heroic Autobots and the evil Decepticons, comes to Earth, with a clue to the ultimate power held by a teenager.
- Four people and their otherworldly frienemy struggle in the afterlife to define what it means to be good.
- A troubled youth becomes embroiled in the lives of a close-knit group of people in the wealthy, upper-class neighborhood of Newport Beach, Orange County, California.
- The famed monster hunter is sent to Transylvania to stop Count Dracula, who is using Dr. Frankenstein's research and a werewolf for nefarious purposes.
- Common people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.
- A Phoenix secretary embezzles $40,000 from her employer's client, goes on the run and checks into a remote motel run by a young man under the domination of his mother.
- A deranged scientist escapes from prison and recruits Dracula, Frankenstein's monster and the Wolf Man to get revenge on his behalf.
- Two high-school nerds use a computer program to literally create the perfect woman, who promptly turns their lives upside-down.
- The vampire Angel, cursed with a soul, moves to Los Angeles and aids people with supernatural-related problems while questing for his own redemption.
- A FedEx executive undergoes a physical and emotional transformation after crash landing on a deserted island.
- The lives and tragedies of the Braverman family tree.
- Detectives from NYPD's 15th Precinct investigate homicides within their precinct.
- In the deep south during the 1930s, three escaped convicts search for hidden treasure while a relentless lawman pursues them.
- A marksman living in exile is coaxed back into action after hearing of a plot to kill the President. After being-double crossed for the attempt and on the run, he sets out for the real killer and the truth.
- Jon Arbuckle buys a second pet, a dog named Odie. However, Odie is then abducted and it is up to Jon's cat, Garfield, to find and rescue the canine.
- Jack Sparrow races to recover the heart of Davy Jones to avoid enslaving his soul to Jones' service, as other friends and foes seek the heart for their own agenda as well.
- A research team is sent to the Jurassic Park Site B island to study the dinosaurs there, while an InGen team approaches with another agenda.
- A fearless, globe-trotting, terrorist-battling secret agent has his life turned upside down when he discovers his wife might be having an affair with a used-car salesman while terrorists smuggle nuclear war heads into the United States.
- NASA must devise a strategy to return Apollo 13 to Earth safely after the spacecraft undergoes massive internal damage putting the lives of the three astronauts on board in jeopardy.
- Jake Blues rejoins with his brother Elwood after being released from prison, but the duo has just days to reunite their old R&B band and save the Catholic home where the two were raised, outrunning the police as they tear through Chicago.
- The misadventures of a suburban boy, family and friends.
- The crew of the ship Serenity try to evade an assassin sent to recapture telepath River.
- A nurse, a policeman, a young married couple, a salesman and other survivors of a worldwide plague that is producing aggressive, flesh-eating zombies, take refuge in a mega Midwestern shopping mall.
- Peter Parker is beset with troubles in his failing personal life as he battles a former brilliant scientist named Otto Octavius.
- Melinda Gordon, a newly married woman, possesses the gift of communicating with the dead. With her best friend Andrea's assistance, she helps the earthbound spirits to find peace and cross over.
- Jack Sparrow and Barbossa embark on a quest to find the elusive fountain of youth, only to discover that Blackbeard and his daughter are after it too.
- A volcanologist arrives at a countryside town recently named the second-most desirable place to live in America, and discovers that a nearby long-dormant volcano may awaken at any moment.
- Atticus Finch, a widowed lawyer in Depression-era Alabama, defends a Black man against an undeserved rape charge, and tries to educate his young children against prejudice.
- Stories of the journeys of a wagon train as it leaves post-Civil War Missouri on its way to California through the plains, deserts, and Rocky Mountains.
- After a severely injured test pilot is rebuilt with nuclear-powered bionic limbs and implants, he serves as an intelligence agent.
- Three actors accept an invitation to a Mexican village to perform their onscreen bandit fighter roles, unaware that it is the real thing.
- Captain Barbossa, Will Turner and Elizabeth Swann must sail off the edge of the map, navigate treachery and betrayal, find Jack Sparrow, and make their final alliances for one last decisive battle.
- The cases of an easy-going ex-convict turned private investigator.
- Batman and Robin try to keep their relationship together even as they must stop Mr. Freeze and Poison Ivy from freezing Gotham City.